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Bovine Collagen Type X Alpha 1 Chain (COL10A1) ELISA Kit-Sandwich

Cat. No.EK11F630

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Bovine Collagen Type X Alpha 1 Chain (COL10A1) ELISA Kit-Sandwich is designed for the quantitative determination of Bovine Collagen Type X Alpha 1 Chain (COL10A1) in serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Bovine COL10A1.
Target Species Bovine
Species Reactivity Bovine
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 10%
Assay Time Around 270 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids.

Target Information

Bovine Collagen type X alpha 1 chain is encoded by the COL10A1 gene in cattle. It is a short-chain collagen expressed by hypertrophic chondrocytes during endochondral ossification. Collagen type X has a short triple helical collagen domain flanked by the N-terminal NC2 and the C-terminal NC1 domains. As a specific marker of hypertrophic chondrocytes, COL10A1 is critical for endochondral bone formation, and mutations and altered expression of COL10A1 are often associated with abnormal chondrocyte hypertrophy in many skeletal diseases.

Target/Biomarker Bovine COL10A1
Target Synonym collagen type X alpha 1 chain; collagen alpha-1(X) chain; collagen, type X, alpha 1 (Schmid metaphyseal chondrodysplasia); type X collagen alpha 1
Gene ID 282416
UniProt ID P23206

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Gu, J. et al. Identification and characterization of the novel Col10a1 regulatory mechanism during chondrocyte hypertrophic differentiation. Cell death & disease. 2014, 5: e1469-e1469.
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