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Mouse Selectin, Platelet (SELP) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Selectin, Platelet (SELP) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse SELP in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
P-selectin is a Ca2±dependent receptor on myeloid cells that binds to carbohydrates on neutrophils and monocytes, facilitating the interaction between activated endothelial cells or platelets and leukocytes. It specifically recognizes the ligand sialyl-Lewis X and plays a role in the rapid rolling of leukocytes over vascular surfaces during the initial stages of inflammation through its interaction with SELPLG. Additionally, P-selectin is involved in cell-cell interactions and cell adhesion through interactions with integrin alpha-IIb/beta3 (ITGA2B:ITGB3) and integrin alpha-V/beta3 (ITGAV:ITGB3). In mice, P-selectin has several functions, including promoting atherosclerosis, the inflammatory response, tumor metastasis, thrombosis, and immune regulation. In a mouse breast cancer model, P-selectin enhances tumor cell migration by binding to glycoproteins on the tumor cell surface.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.