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Mouse Selectin, Platelet (SELP) ELISA Kit-Sandwich

Cat. No.EK5F213

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Selectin, Platelet (SELP) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse SELP in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Selectin, Platelet (SELP).
Target Species Mouse
Species Reactivity Mouse
Detection Range 78.25-5000 pg/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

P-selectin is a Ca2±dependent receptor on myeloid cells that binds to carbohydrates on neutrophils and monocytes, facilitating the interaction between activated endothelial cells or platelets and leukocytes. It specifically recognizes the ligand sialyl-Lewis X and plays a role in the rapid rolling of leukocytes over vascular surfaces during the initial stages of inflammation through its interaction with SELPLG. Additionally, P-selectin is involved in cell-cell interactions and cell adhesion through interactions with integrin alpha-IIb/beta3 (ITGA2B:ITGB3) and integrin alpha-V/beta3 (ITGAV:ITGB3). In mice, P-selectin has several functions, including promoting atherosclerosis, the inflammatory response, tumor metastasis, thrombosis, and immune regulation. In a mouse breast cancer model, P-selectin enhances tumor cell migration by binding to glycoproteins on the tumor cell surface.

Target/Biomarker Mouse SELP
Target Synonym CD62P; P-Selectin; PSEL; GMP140; LECAM3; GRMP; GMRP; PADGEM; Leukocyte-endothelial cell adhesion molecule 3; Platelet activation dependent granule-external membrane
Gene ID 20344
UniProt ID Q01102

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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