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Mouse Podocan (PODN) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Podocan (PODN) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse PODN in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Podocan acts as a negative regulator of cell proliferation and migration, particularly in smooth muscle cells. As a member of the small leucine-rich proteoglycan (SLRP) family, Podocan's functions in mice encompass several areas, including skeletal muscle regeneration, the migration and proliferation of vascular smooth muscle cells, and interactions with the TGF-β signaling pathway. In mice, Podocan is crucial for skeletal muscle regeneration. Research has demonstrated that Podocan promotes the differentiation of C2C12 myoblasts and enhances the differentiation capacity of skeletal muscle satellite cells by inhibiting the TGF-β signaling pathway. In models of cardiac pressure overload, mice lacking Podocan exhibit more pronounced cardiac hypertrophy.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.