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Mouse Integrin Alpha 4 (ITGa4) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Integrin Alpha 4 (ITGa4) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse ITGa4 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Integrins alpha-4/beta-1 (VLA-4 or LPAM-2) and alpha-4/beta-7 (LPAM-1) serve as receptors for fibronectin, specifically recognizing one or more domains within the alternatively spliced CS-1 and CS-5 regions. They also function as receptors for VCAM1, with integrin alpha-4/beta-1 recognizing the Q-I-D-S sequence in VCAM1. Integrin α-4 plays a crucial role in the development of mouse skeletal muscle and is involved in the regeneration of neuronal axons within the nervous system. Research has shown that following sciatic nerve injury in mice, the immune response involving integrin α-4 is significantly enhanced, and its cytoplasmic domain is essential for neurite growth.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.