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Mouse Gastrin (GT) ELISA Kit-Competitive
Product Overview
BioVenic Mouse Gastrin (GT) ELISA Kit-Competitive is designed for the quantitative determination of Mouse GT in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Competitive ELISA method. For research use only.
Specifications
Target Information
Gastrin prompts the gastric mucosa to produce and secrete hydrochloric acid and stimulates the pancreas to release its digestive enzymes. Additionally, it encourages smooth muscle contraction and enhances blood flow and water secretion in the stomach and intestines. As the primary driver of gastric acid secretion, gastrin stimulates hydrochloric acid production by targeting parietal cells. Mice lacking gastrin exhibit a marked decrease in basal gastric acid secretion and a diminished response to histamine, cholinergic, and gastrin stimulation. In mouse models with Helicobacter pylori infection or those treated with chemical carcinogens, increased gastrin levels are linked to gastric mucosal hyperplasia and the progression of gastric cancer.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Jiang, Yannan, and Yingyan Yu. "Transgenic and gene knockout mice in gastric cancer research." Oncotarget vol. 8,2 (2017): 3696-3710.