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Mouse Nuclear Factor, Erythroid Derived 2 Like Protein 2 (NFE2L2) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Nuclear Factor, Erythroid Derived 2 Like Protein 2 (NFE2L2) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse NFE2L2 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Nuclear factor erythroid 2-related factor 2 (NFE2L2) is a crucial transcription factor involved in combating oxidative stress. It attaches to antioxidant response elements (ARE) in the promoter regions of numerous protective genes, including phase 2 detoxifying enzymes, and stimulates their expression to neutralize reactive electrophiles. As a vital regulator, NFE2L2 manages the expression of antioxidant genes through AREs, safeguarding cells from oxidative stress damage. For instance, mice lacking NFE2L2 exhibit higher oxidative stress levels and more severe cellular damage under oxidative stress conditions, highlighting NFE2L2's essential role in sustaining cellular antioxidant defenses.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Porreca, Immacolata et al. "Cross-species toxicogenomic analyses and phenotypic anchoring in response to groundwater low-level pollution." BMC genomics vol. 15,1 1067. 5 Dec. 2014.