This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Mouse Discs, Large Homolog 4 (DLG4) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Discs, Large Homolog 4 (DLG4) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse DLG4 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Disks large homolog 4 is a postsynaptic scaffolding protein essential for synaptogenesis and synaptic plasticity, as it provides a platform for clustering key synaptic proteins at the postsynaptic site. Through the protein PSD-95 it encodes, DLG4 plays a significant role in synaptic signaling, neurodevelopment, metabolic regulation, and the development of neuropsychiatric disorders in mice. DLG4 functions at the postsynaptic membrane via PSD-95 by interacting with neurotransmitter receptors like NMDA and AMPA receptors, thereby regulating neuronal synaptic signaling. In models of hypertension-induced cognitive decline, DLG4 expression levels are reduced, which may correlate with abnormal cerebral hemodynamics, neuronal damage, and cognitive decline.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Wan, Chong et al. "The new mechanism of cognitive decline induced by hypertension: High homocysteine-mediated aberrant DNA methylation." Frontiers in cardiovascular medicine vol. 9 928701. 24 Oct. 2022.