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Mouse Chemokine C-C-Motif Receptor 6 (CCR6) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Chemokine C-C-Motif Receptor 6 (CCR6) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse CCR6 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
C-C chemokine receptor type 6 (CCR6) serves as a receptor for the C-C type chemokine CCL20. Upon binding to CCL20, it transmits a signal by elevating intracellular calcium ion levels. In mice, CCR6 primarily influences bone marrow metabolism, osteoblast differentiation, and immune system regulation. It impacts bone marrow metabolism by modulating the expression of osteoblast-related genes, such as Osterix and OPG/RANKL. Mice lacking CCR6 exhibit reduced osteoblast activity, evidenced by decreased alkaline phosphatase (ALP) activity, impaired mineralization ability, and hindered differentiation of osteoblasts.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.