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Mouse Dolichyl Diphosphooligosaccharide Protein Glycosyltransferase (DDOST) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Dolichyl Diphosphooligosaccharide Protein Glycosyltransferase (DDOST) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse DDOST in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Dolichyl-diphosphooligosaccharide-protein glycosyltransferase 48 kDa subunit is part of the oligosaccharyl transferase (OST) complex, which facilitates the initial transfer of a specific glycan (Glc3Man9GlcNAc2 in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. This process represents the first step in protein N-glycosylation. In mice, DDOST is expressed at low levels, particularly in the brain. A loss or dysfunction of DDOST can result in various genetic diseases, such as congenital disorders of glycosylation.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Tu, Yi et al. "MITA oligomerization upon viral infection is dependent on its N-glycosylation mediated by DDOST." PLoS pathogens vol. 18,11 e1010989. 30 Nov. 2022.