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Mouse Succinate Dehydrogenase Complex Subunit B (SDHB) ELISA Kit-Sandwich

Cat. No.EK6F493

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Succinate Dehydrogenase Complex Subunit B (SDHB) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse SDHB in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Succinate Dehydrogenase Complex Subunit B (SDHB).
Target Species Mouse
Species Reactivity Mouse
Detection Range 0.17-10 ng/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

The succinate dehydrogenase [ubiquinone] iron-sulfur subunit, located in the mitochondria, is an iron-sulfur protein (IP) component of the succinate dehydrogenase complex, known as mitochondrial respiratory chain complex II. This subunit is crucial for transferring electrons from succinate to ubiquinone (coenzyme Q), playing a vital role in sustaining mitochondrial function. In aged mice, mitochondrial transplantation can significantly boost the expression of mitochondrial complex II proteins in the hippocampus, thereby enhancing mitochondrial function. A deficiency or decline in Sdhb functionality results in decreased activity of mitochondrial complex II, adversely affecting cellular energy metabolism and the oxidative phosphorylation process.

Target/Biomarker Mouse SDHB
Target Synonym SDH1; SDH; Ip; Iron Sulfur; Iron-sulfur subunit of complex II; Succinate dehydrogenase [ubiquinone] iron-sulfur subunit; mitochondrial
Gene ID 67680
UniProt ID Q9CQA3

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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