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Mouse Nitric Oxide Synthase 3, Endothelial (NOS3) ELISA Kit-Sandwich

Cat. No.EK5F294

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Nitric Oxide Synthase 3, Endothelial (NOS3) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse NOS3 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Nitric Oxide Synthase 3, Endothelial (NOS3).
Target Species Mouse
Species Reactivity Mouse
Detection Range 1.57-100 ng/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Nitric oxide synthase 3 (NOS3) generates nitric oxide (NO), which facilitates vascular smooth muscle relaxation via a cGMP-mediated signal transduction pathway. NO is involved in VEGF-induced angiogenesis in coronary vessels and aids in blood clotting by activating platelets. NOS3 may have significant roles in both normal and abnormal limb development. In mice, the primary functions of NOS3 are related to the cardiovascular system, inflammatory response, and metabolic regulation. NOS3 also plays a crucial role in inflammation; for instance, inhibiting NOS3 in a cerebral ischemia-reperfusion model can reduce neuronal death and brain damage.

Target/Biomarker Mouse NOS3
Target Synonym ECNOS; NOS III; E-NOS; C-NOS; ENOS; CNOS; Constitutive NOS
Gene ID 18127
UniProt ID P70313

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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