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Mouse B-Lymphocyte Activation Antigen B7-2 (LAB7-2) ELISA Kit-Sandwich

Cat. No.EK5F30

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse B-Lymphocyte Activation Antigen B7-2 (LAB7-2) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse LAB7-2 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse B-Lymphocyte Activation Antigen B7-2 (LAB7-2).
Target Species Mouse
Species Reactivity Mouse
Detection Range 0.17-10 ng/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

T-lymphocyte activation antigen CD86, also known as B-Lymphocyte Activation Antigen B7-2, is a receptor crucial for providing the costimulatory signal necessary for T-lymphocyte proliferation and interleukin-2 production through its interaction with CD28 or CTLA-4. It may play a pivotal role in the initial stages of T-cell activation and costimulation of naive T-cells, influencing the decision between immunity and anergy within 24 hours of activation. CD86 also regulates B cell function, particularly in controlling the level of IgG1 production. Upon engagement with CD40, it activates the NF-kappa-B signaling pathway through phospholipase C and protein kinase C activation.

Target/Biomarker Mouse LAB7-2
Target Synonym CD86; B7-2; B70; FUN-1; CD28LG2; CD28 Antigen Ligand 2;B7-2 Antigen; CTLA-4 counter-receptor B7.2
Gene ID 12524
UniProt ID P42082

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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