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Bovine Cyclic GMP-AMP Synthase (CGAS) ELISA Kit-Sandwich
Product Overview
BioVenic Bovine Cyclic GMP-AMP Synthase (CGAS) ELISA Kit-Sandwich is designed for the quantitative determination of Bovine Cyclic GMP-AMP Synthase (CGAS) in serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
The cytosolic DNA sensor cyclic GMP-AMP synthase (cGAS) recognises exogenous double-stranded DNA and produces 2'3'-cyclic GMP-AMP (2'3'-cGAMP), activating the stimulator of interferon genes (STING) and innate immunity. The resulting cGAMP functions as a second messenger that binds to and activates the endoplasmic reticulum protein STING, triggering the production of type-I interferons. Research has shown that bo-cGAS recognises exogenous double-stranded DNA and triggers the STING-dependent IFN-β production pathway.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.