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Recombinant Mouse Galectin-3-Binding Protein (Lgals3bp), N-His
Product Overview
BioVenic's Recombinant Mouse Galectin-3-Binding Protein (Lgals3bp), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 66.0 kDa. The purity is> 90%.
Specifications
Target Information
Mouse Galectin-3-Binding Protein (Lgals3bp) is a multifunctional glycoprotein involved in immune responses and cancer. It is highly glycosylated and secreted, often upregulated in various cancers, including colorectal and prostate cancer. Lgals3bp binds to CD33-related Siglecs, inhibiting neutrophil activation and contributing to immune evasion in tumors. Additionally, it suppresses colon inflammation and tumorigenesis by downregulating the TAK1-NF-κB signaling pathway. This protein also plays a role in cell adhesion, macrophage activation, and apoptosis.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10 mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.