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Recombinant Mouse Intelectin 1 (Itln1)
Product Overview
BioVenic's Recombinant Mouse Intelectin 1 (Itln1) is a recombinant protein expressed from E.coli. Its predicted molecular weight is n/a. The purity is> 95%.
Specifications
Target Information
Mouse Intelectin 1 (Itln1) is a carbohydrate-binding lectin primarily expressed in the small intestine, particularly in Paneth cells. It plays a role in innate immunity by binding to microbial glycans and is involved in the regulation of the gut microbiota. Itln1 has been implicated in various physiological processes, including the modulation of the mucus barrier and the immune response to parasitic infections. Additionally, Itln1 is associated with metabolic diseases such as obesity and type 2 diabetes, where its expression levels are inversely correlated with body mass index. In mouse models, Itln1 knockout mice exhibit increased susceptibility to experimentally induced colitis, highlighting its role in maintaining gut homeostasis.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.