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Recombinant Mouse Complement Component 1 Q Subcomponent-binding Protein, Mitochondrial (C1qbp), N-His
Product Overview
BioVenic's Recombinant Mouse Complement Component 1 Q Subcomponent-binding Protein, Mitochondrial (C1qbp), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 25.0 kDa. The purity is> 90%.
Specifications
Target Information
Mouse Complement Component 1 Q Subcomponent-binding Protein, Mitochondrial (C1qbp) is a multifunctional protein involved in mitochondrial homeostasis, oxidative phosphorylation, and immune responses. It is essential for maintaining mitochondrial plasticity and metabolic fitness in T cells, thereby enhancing their antitumor function. C1qbp also plays a role in dendritic cell metabolism and maturation, influencing immune responses. In cancer, C1qbp is implicated in breast cancer metastasis, where it regulates cancer cell chemotaxis and is associated with distant metastasis and TNM stages. Additionally, C1qbp interacts with cyclophilin D to inhibit mitochondrial permeability transition and protect cells from oxidative stress-induced cell death. It is a potential therapeutic target in cancer and mitochondrial diseases.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10 mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.