Recombinant Mouse CD160 Antigen (CD160 ), C-His

Mouse CD160 Antigen, or CD160, is an antigen expressed on natural killer cells and T cells, involved in immune response regulation. In mouse experiments, CD160 is used to study immune cell activation and function. CD160 is a glycoprotein that can interact with various ligands, including MHC class I molecules, to modulate the activity of immune cells. In natural killer cells, CD160 can deliver inhibitory or activating signals, depending on the context, thereby regulating the cytotoxicity and cytokine production of these cells. In T cells, CD160 expression is associated with terminally differentiated effector cells and may influence their survival and function. Research on CD160 has also revealed its potential role in immune evasion by tumors, as some cancer cells can upregulate MHC class I expression to engage CD160 and inhibit antitumor immune responses. Understanding the dual regulatory functions of CD160 in different immune cell populations is essential for developing strategies to modulate immune responses in infectious diseases, cancer, and autoimmune conditions.