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Recombinant Bovine Ubiquitin-Like Protein ISG15 (ISG15), N-His

Cat. No.AP9C509

Product TypeAnimal Proteins

Size

Product Overview

BioVenic's Recombinant Bovine Ubiquitin-Like Protein ISG15 (ISG15), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 20.7 kDa. The purity is>90% (SDS-PAGE).

Specifications

Type Recombinant Protein
Species Bovine
Expression System E.coli
Purity >90% (SDS-PAGE)
Endotoxin < 1 EU/µg
Predicted Molecular Weight 20.7 kDa
Molecular Weight 21 kDa
Physical State Lyophilized
Formulation 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.

Target Information

Bovine ubiquitin-like protein ISG15 is a protein that is expressed in response to Type 1 Interferon (IFN-α/β) signaling and is involved in innate immune responses to viral and/or microbial infections. It has three distinct biochemical activities: as a posttranslational modifier, attenuating IFN-α/β signaling, and as an extracellular signaling molecule promoting Type 2 Interferon (IFN-γ) secretion by Natural Killer (NK) cells. In cattle, ISG15 plays a role in antiviral responses and immune regulation.

Protein Bovine Ubiquitin-Like Protein ISG15 (ISG15)
Protein Synonym G1P2; IFI15; ISG15; Interferon Alpha-Inducible Protein clone IFI-15K; Interferon Induced Protein 15; Interferon-induced 17 kDa protein
Gene ID 281871
UniProt ID O02741

Shipping and Storage

This product is shipped with dry ice. It is recommended to aliquot as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months. Avoid repeated freezing and thawing.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimise freeze-thaw cycles.
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