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Recombinant Mouse Calcitonin Gene-Related Peptide 2 (Calcb), N-His

Cat. No.AP4C364

Product TypeAnimal Proteins

Size

Product Overview

BioVenic's Recombinant Mouse Calcitonin Gene-Related Peptide 2 (Calcb), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 44.6 kDa. The purity is> 90%.

Specifications

Type Recombinant Protein
Species Mouse
Expression System E.coli
Purity > 90%
Endotoxin < 1.0 EU/μg
Predicted Molecular Weight 44.6 kDa
Physical State Lyophilized
Formulation PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.

Target Information

In mice, Calcitonin Gene-Related Peptide 2 (Calcb) is a neuropeptide involved in various physiological processes. It is expressed in sensory neurons and has immunoregulatory functions, including modulating T cell responses and cytokine production. Calcb can influence the balance between Th1, Th2, and Th17 immune responses through its actions on endothelial cells. It also plays a role in bone metabolism, promoting osteoblast differentiation and bone formation via the Hippo signaling pathway. Additionally, Calcb is implicated in neurogenic inflammation and pain regulation, with potential applications in treating conditions like migraine. In skin, Calcb can upregulate melanogenesis and enhance melanocyte dendricity. Overall, Calcb is a multifunctional peptide with diverse applications in research, particularly in immunology, neurology, and dermatology.

Protein Mouse Calcitonin Gene-Related Peptide 2 (Calcb)
Protein Synonym Beta-type CGRP; Calcitonin gene-related peptide II
EC No. Q99MP3

Shipping and Storage

This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10 mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.
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