Recombinant Chicken Homeobox Protein Hox-B3 (HOXB3)

Chicken Homeobox Protein Hox-B3 (HOXB3) is a transcription factor that plays a crucial role in embryonic development, particularly in the anterior-posterior axis patterning. It is part of the Hox gene cluster, which is highly conserved across species and essential for providing cells with specific positional identities. HOXB3 is involved in the regulation of cell proliferation and differentiation in various tissues, including the central nervous system, heart, and limbs. In chickens, HOXB3 is expressed in early developmental stages and is critical for the proper formation of these structures. Abnormal expression of HOXB3 has been implicated in developmental disorders and certain cancers, highlighting its importance in maintaining normal developmental processes.