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Rabbit Anti-Mouse Membrane Cofactor Protein (MCP) Polyclonal Antibody

Cat. No.VD3N395

Product TypeVeterinary Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for mouse membrane cofactor protein. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse membrane cofactor protein.

Specifications

Application WB; IHC; ICC; IP
Clonality Polyclonal
Classification Primary Antibody
Clone C1N146
Host Rabbit
Target Species Mouse
Species Reactivity Mouse
Specificity Mouse Membrane Cofactor Protein
Isotype IgG
Immunogen Recombinant protein of mouse membrane cofactor protein
Purification Purified by Protein A
Concentration 0.5 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.05% Proclin 300
Buffer 0.01M Phosphate Buffered Saline, pH 7.4, with 50% glycerol
Physical State Liquid

Target Information

Mouse Membrane Cofactor Protein (MCP), also known as CD46, is a regulator of complement activation (RCA) protein expressed on the surface of nucleated cells. It functions as a cofactor for factor I, facilitating the degradation of C3b and C4b, thereby protecting cells from complement-mediated damage. MCP plays a vital role in maintaining immune homeostasis by preventing excessive complement activation. In addition to its protective role, MCP is involved in cell signaling pathways and contributes to immune regulation.

Target Mouse Membrane Cofactor Protein
Target Synonym CD46; MIC10; TLX; TRA2; Trophoblast leukocyte common antigen
Gene ID 17221
UniProt ID O88174

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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