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Rabbit Anti-Mouse Fibroblast Growth Factor 21 (FGF21) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse fibroblast growth factor 21. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse fibroblast growth factor 21.
Specifications
Target Information
Mouse fibroblast growth factor 21 (FGF21) is a 20-kDa secreted metabolic hormone predominantly expressed in murine liver, adipose tissue, and skeletal muscle. It signals via FGFR1/β-Klotho co-receptor complexes, activating downstream pathways to regulate glucose/lipid metabolism, energy expenditure, and ketogenesis. Critical for murine metabolic homeostasis, it enhances insulin sensitivity, promotes fatty acid oxidation, and mitigates obesity-induced metabolic dysfunction. Dysregulated expression associates with type 2 diabetes, non-alcoholic fatty liver disease, and obesity in murine models. As a key mediator of systemic metabolic regulation, mouse FGF21 is a critical target for studying metabolic pathobiology and developing therapeutics for metabolic syndrome and related disorders.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.