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Rabbit Anti-Mouse Epiregulin (EREG) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse epiregulin. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse epiregulin.
Specifications
Target Information
Mouse epiregulin (EREG) is a 19-kDa secreted growth factor belonging to the EGF family, predominantly expressed in mouse epithelial tissues (skin, intestine, lung) and activated immune cells. It binds to EGF receptors (EGFR/ErbB1, ErbB4) to activate downstream signaling (MAPK, PI3K-AKT), regulating cell proliferation, differentiation, and epithelial barrier repair. Critical for murine tissue homeostasis, wound healing, and mucosal defense, it also modulates inflammatory responses and tumorigenesis in pathological contexts. Dysregulated expression associates with inflammatory disorders, epithelial hyperplasia, and various cancers. As a key mediator of epithelial biology and growth factor signaling, mouse EREG is a critical target for studying tissue repair, inflammatory pathologies, and cancer therapeutics.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.