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Rabbit Anti-Mouse T-Cell Immunoreceptor with Ig and ITIM Domains Protein (TIGIT) Polyclonal Antibody

Cat. No.VD3N488

Product TypeVeterinary Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for mouse T-cell immunoreceptor with Ig and ITIM domains protein. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse T-cell immunoreceptor with Ig and ITIM domains protein.

Specifications

Application WB; IHC; ICC; IP
Clonality Polyclonal
Classification Primary Antibody
Clone C1N239
Host Rabbit
Target Species Mouse
Species Reactivity Mouse
Specificity Mouse T-Cell Immunoreceptor With Ig and ITIM Domains Protein
Isotype IgG
Immunogen Recombinant protein of mouse T-cell immunoreceptor with Ig and ITIM domains protein
Purification Purified by Protein A
Concentration 0.48 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.05% Proclin 300
Buffer 0.01M Phosphate Buffered Saline, pH 7.4, with 50% glycerol
Physical State Liquid

Target Information

Mouse T-Cell Immunoreceptor with Ig and ITIM Domains (TIGIT) is a co-inhibitory receptor expressed on T cells and natural killer (NK) cells. It interacts with its ligands, CD155 and CD112, to modulate immune responses. TIGIT plays a crucial role in regulating T cell activation and maintaining immune homeostasis. Its engagement can inhibit T cell proliferation and cytokine production, contributing to immune tolerance. TIGIT is an important target for studying immune regulation and developing therapeutic strategies in mouse models.

Target Mouse T-Cell Immunoreceptor With Ig and ITIM Domains Protein
Target Synonym VSIG9; VSTM3; V-Set and Immunoglobulin Domain Containing 9; V-Set and Transmembrane Domain Containing 3
Gene ID 100043314
UniProt ID P86176

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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