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Mouse Transglutaminase 3, Epidermal (TGM3) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Transglutaminase 3, Epidermal (TGM3) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse TGM3 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Protein-glutamine gamma-glutamyltransferase E (TGM3) catalyzes the calcium-dependent formation of isopeptide cross-links between glutamine and lysine residues in various proteins, as well as the attachment of polyamines to proteins. It plays a key role in forming the cornified envelope (CE), a specialized structure consisting of covalently cross-linked proteins beneath the plasma membrane of terminally differentiated keratinocytes. TGM3 is crucial for the development of mouse skin and hair. Research has shown that mice lacking TGM3 exhibit hair abnormalities, such as thinning, twisting, and slower growth, which resemble the characteristics of human uncombed hair syndrome (UHCS).
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Chermnykh, Elina S et al. "Transglutaminase 3: The Involvement in Epithelial Differentiation and Cancer." Cells vol. 9,9 1996. 30 Aug. 2020.