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Mouse Gamma-Aminobutyric Acid (gABA) ELISA Kit-Competitive

Cat. No.EK6F765

Product TypeAnimal Immunoassay Kits

Size 96T

Product Overview

BioVenic Mouse Gamma-Aminobutyric Acid (gABA) ELISA Kit-Competitive is designed for the quantitative determination of Mouse gABA in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Competitive ELISA method. For research use only.

Specifications

Assay Type ELISA-Competitive
Specificity The assay kit is specific for Mouse Gamma-Aminobutyric Acid (gABA).
Target Species Mouse
Species Reactivity Mouse
Detection Range 31.25-2000 pg/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

GABA is crucial in the nervous system of mice, influencing neuronal development and synaptic plasticity. Research indicates that while the functional differences between the two subtypes of glutamate decarboxylase (GAD65 and GAD67), the enzymes responsible for synthesizing GABA, remain unclear, gene targeting studies can help elucidate their specific roles. Additionally, GABA receptors, such as GABA_A and GABA_B, are vital in regulating anxiety, memory, and learning processes. Beyond its neurological functions, GABA also significantly impacts metabolic functions in mice. It enhances insulin sensitivity, lowers blood sugar levels, and promotes the browning of adipose tissue, thereby addressing obesity and metabolic syndrome. Furthermore, GABA positively affects intestinal health and energy metabolism by improving the composition of the intestinal microbiota through increased production of short-chain fatty acids (SCFAs).

Target/Biomarker Mouse gABA
Target Synonym 4-Aminobutyric Acid

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Ma, Xiaoyi et al. "Gamma-Aminobutyric Acid Promotes Beige Adipocyte Reconstruction by Modulating the Gut Microbiota in Obese Mice." Nutrients vol. 15,2 456. 15 Jan. 2023.
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