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Mouse Sclerostin (SOST) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Sclerostin (SOST) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse SOST in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Sclerostin is a negative regulator of bone growth, primarily inhibiting Wnt signaling and bone formation. In mice, its main function is to suppress bone formation via the Wnt/β-catenin signaling pathway, thereby influencing bone health, metabolism, and disease processes through various mechanisms. In transgenic mice, overexpression of sclerostin results in reduced bone mass, diminished bone formation, and decreased bone strength. Additionally, sclerostin expression is observed in both osteoblasts and osteoclasts, particularly in aged mice, where osteoclast-secreted sclerostin levels significantly increase, potentially further inhibiting bone formation.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.