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Mouse Polyamine Oxidase (PAOX) ELISA Kit-Sandwich

Cat. No.EK6F371

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Polyamine Oxidase (PAOX) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse PAOX in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Polyamine Oxidase (PAOX).
Target Species Mouse
Species Reactivity Mouse
Detection Range 78.25-5000 pg/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Peroxisomal N(1)-acetyl-spermine/spermidine oxidase is a flavoenzyme responsible for converting N1-acetylspermine into spermidine, playing a critical role in polyamine back-conversion. In mice, PAOX primarily regulates polyamine metabolism, impacting cellular oxidative balance and inflammatory responses, and is linked to the onset and progression of various diseases. In mouse models of intervertebral disc degeneration (IDD), increased PAOX expression is identified as a key factor accelerating disease progression. Long-term spermine supplementation can effectively reduce PAOX upregulation, thereby diminishing oxidative stress and slowing IDD progression.

Target/Biomarker Mouse PAOX
Target Synonym PAO; Peroxisomal N(1)-Acetyl-Spermine/Spermidine Oxidase(Exo-N4-Amino)
Gene ID 212503
UniProt ID Q8C0L6

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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