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Mouse Low Density Lipoprotein Receptor (LDLR) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Low Density Lipoprotein Receptor (LDLR) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse LDLR in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
The Low Density Lipoprotein Receptor (LDLR) binds to low density lipoprotein (LDL), which is the primary cholesterol-carrying lipoprotein in plasma, facilitating its transport into cells via endocytosis. For internalization to occur, the receptor-ligand complexes need to cluster into clathrin-coated pits. Additionally, LDLR forms a ternary complex with PGRMC1 and TMEM97 receptors, enhancing LDLR-mediated LDL internalization. In mice, LDLR is involved in cholesterol metabolism, disease occurrence, signal transduction, neuroprotection, and more. Research has demonstrated that LDLR-deficient mouse models experience a significant reduction in atherosclerosis, suggesting that LDLR promotes the development of this condition.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.