This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Mouse Interferon Regulatory Factor 5 (IRF5) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Interferon Regulatory Factor 5 (IRF5) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse IRF5 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Interferon regulatory factor 5 (IRF5) is a transcription factor essential for innate immunity, primarily by activating the expression of type I interferon (IFN) genes, IFNA and INFB, and inflammatory cytokines following signals from endolysosomal toll-like receptors TLR7, TLR8, and TLR9. It regulates these genes by binding to an interferon-stimulated response element (ISRE) in their promoters. In mice, IRF5 is pivotal in regulating the production of type I interferon, contributing to inflammatory responses and the development of autoimmune diseases. In a mouse model, the absence of IRF5 significantly prolonged the lifespan of MRL/lpr mice and decreased the incidence of glomerulonephritis and the production of SLE-related autoantibodies.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.