This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Mouse Glucuronidase Beta (GUSb) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Glucuronidase Beta (GUSb) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse GUSb in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Beta-glucuronidase is crucial for the breakdown of dermatan and keratan sulfates. In mice, its function extends beyond serving as a marker for gene expression analysis; it also plays roles in disease model research, hormone regulation, and biochemical reactions. In mouse models, β-glucuronidase activity is closely linked to certain genetic disorders. For instance, a genetic defect in mice that resembles human mucopolysaccharidosis type VII (MPS VII) results in significantly reduced β-glucuronidase activity, leading to lysosomal storage disease. Additionally, in mice, the expression of β-glucuronidase is influenced by hormones. Testosterone, for example, can induce the production of β-glucuronidase mRNA in the kidneys, thereby enhancing its activity.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.