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Mouse Chemokine C-C-Motif Receptor 10 (CCR10) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Chemokine C-C-Motif Receptor 10 (CCR10) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse CCR10 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
C-C chemokine receptor type 10 acts as a receptor for the chemokines SCYA27 and SCYA28, transmitting signals by elevating intracellular calcium ion levels. In mice, CCR10 plays several crucial roles, including regulating the balance of immune cells in the skin, facilitating the migration and localization of lymphocytes, participating in inflammatory responses, and influencing tumor immunity processes. By binding to the skin-specific ligand CCL27, CCR10 supports the migration and maintenance of skin-resident T cells, including Treg and Teff cells. In mice lacking CCR10 (CCR10−/−), there's an imbalance in Treg and Teff cell numbers in the skin, leading to heightened innate and memory immune responses.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.