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Mouse Estrogen Receptor Alpha (ERa) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Estrogen Receptor Alpha (ERa) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse ERa in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
The steroid hormone receptor ERR1 binds to an ERR-alpha response element (ERRE), which contains a single consensus half-site, 5'-TNAAGGTCA-3'. It can also bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may serve as an important regulator of the MCAD promoter. Moreover, it binds to the C1 region of the lactoferrin gene promoter and requires dimerization along with the coactivator, PGC-1A, for full activity. The ERRalpha/PGC1alpha complex regulates energy metabolism and induces the expression of PERM1 in skeletal muscle. ERα plays a crucial role in mouse reproduction, behavior, metabolism, bone health, cognitive function, and more. Disruption or abnormalities in these functions often lead to significant physiological and behavioral defects.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.