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Mouse Potassium Voltage-Gated Channel Subfamily KQT Member 1 (KCNQ1) ELISA Kit-Sandwich

Name: Mouse Potassium Voltage-Gated Channel Subfamily KQT Member 1 (KCNQ1) ELISA Kit-Sandwich
SKU: EK6F943
Rating: 5 (1 reviews)

Cat. No.EK6F943

Product TypeAnimal Immunoassay Kits

Size

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Product Overview

BioVenic Mouse Potassium Voltage-Gated Channel Subfamily KQT Member 1 (KCNQ1) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse KCNQ1 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich

Specificity The assay kit is specific for Mouse Potassium Voltage-Gated Channel Subfamily KQT Member 1 (KCNQ1).

Target Species Mouse

Species Reactivity Mouse

Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%

Assay Time Around 90 min

Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

KCNQ1, part of the potassium voltage-gated channel subfamily KQT, acts as a pore-forming element of the voltage-gated potassium (Kv) channel crucial for regulating cardiomyocyte excitability. It is essential for the normal development and function of the myocardium, inner ear, stomach, and colon. In mouse models, the absence or malfunction of KCNQ1 results in various phenotypic alterations. For instance, KCNQ1 knockout mice (KvLQT1-KO) display traits such as cochlear defects, ataxia, and polycythemia. These phenotypes are intricately linked to the role of KCNQ1 in the inner ear, where it helps maintain ion balance, thereby supporting normal hearing.

Target/Biomarker Mouse KCNQ1

Target Synonym Potassium Voltage-Gated Channel Subfamily KQT Member 1; Kcnq1; IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1; KQT-like 1; Voltage-gated potassium channel subunit Kv7.1

Gene ID 16535

UniProt ID P97414

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

Aubin Vega, Mélissa et al. "Function of KvLQT1 potassium channels in a mouse model of bleomycin-induced acute lung injury." Frontiers in physiology vol. 15 1345488. 20 Feb. 2024.