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Mouse Calpastatin (CAST) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Calpastatin (CAST) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse CAST in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Calpastatin is crucial for postmortem meat tenderization and is thought to be involved in muscle protein degradation in living tissues. In mice, calpastatin serves various physiological functions, such as regulating muscle metabolism, inhibiting inflammatory responses, protecting neurons, and enhancing cardiovascular function. In mouse models, it mitigates inflammatory responses by inhibiting calpain activity. For instance, in a multiple sclerosis (MS) model, calpastatin overexpression reduces inflammatory cell infiltration and proinflammatory cytokine release, thereby ameliorating the pathological condition. Additionally, calpastatin exhibits similar effects in sepsis models, enhancing mouse survival rates by reducing inflammation and coagulation disorders.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.