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Mouse Growth Regulated Oncogene Alpha (GROa/CXCL1) ELISA Kit-Sandwich

Cat. No.EK5F220

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Growth Regulated Oncogene Alpha (GROa/CXCL1) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse GROa/CXCL1 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Growth Regulated Oncogene Alpha (GROa/CXCL1).
Target Species Mouse
Species Reactivity Mouse
Detection Range 15.7-1000 pg/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Growth-regulated alpha protein exhibits chemotactic activity for neutrophils, aiding in their activation during inflammation. As a hematoregulatory chemokine, it suppresses hematopoietic progenitor cell proliferation in vitro. In mice, GROα primarily functions as a chemokine and pro-angiogenic factor, playing a crucial role in biological processes such as inflammation, immune regulation, and tissue repair. In a high-fat diet-induced atherosclerosis model, GROα expression was linked to macrophage polarization and the M1 phenotype. Additionally, significant changes in GROα expression were observed in patients with acute respiratory distress syndrome (ARDS), highlighting its potential involvement in immune regulation and inflammatory response.

Target/Biomarker Mouse GROa/CXCL1
Target Synonym CXCL1; GRO1; GROa; GRO-A; MGSA-A; NAP3; SCYB1; Chemokine C-X-C-Motif Ligand 1; Melanoma Growth Stimulating Activity Alpha; Fibroblast Secretory Protein; Neutrophil Activating Protein 3
Gene ID 14825
UniProt ID P12850

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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