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Tacrolimus (FK506) ELISA Kit-Competitive

Product Overview

BioVenic General Tacrolimus (FK506) ELISA Kit-Competitive is designed for the quantitative determination of General Tacrolimus (FK506) in serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids using a Competitive ELISA method. For research use only.

Specifications

Assay Type ELISA-Competitive

Specificity The assay kit is specific for General FK506.

Target Species General

Species Reactivity General

Detection Range 0.16-10 ng/mL

Sensitivity 0.053 ng/mL

Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 10%

Assay Time Around 120 min

Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids.

Target Information

Tacrolimus (FK506) is a potent immunosuppressant used to prevent organ transplant rejection. It is a macrolide lactone that binds to the FK506 binding protein (FKBP) to form a complex. Tacrolimus inhibits calcineurin, an enzyme involved in the production of interleukin-2 (IL-2). By binding to the immunophilin FKBP12, it forms a complex that inhibits calcineurin. This inhibition suppresses T-lymphocyte signalling and reduces IL-2 transcription.

Target/Biomarker General FK506

Target Synonym FK506; Tacrolimus

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.