Mouse Amylase Alpha 1, Salivary (AMY1) ELISA Kit-Sandwich

Hepatic and salivary alpha-amylases are encoded by the same gene, but their mRNAs feature different 5'-UTR sequences. The mouse α-amylase 1 gene (amy1) is primarily expressed in the parotid gland and liver, producing the major salivary amylase enzyme. The expression of this gene is transcriptionally regulated, with a robust promoter in the parotid gland and a less active promoter in the liver. Additionally, the amy1 gene can generate different mRNAs in various tissues through alternative splicing, leading to diverse enzyme products. In experimental settings, α-amylase activity is commonly measured to evaluate salivary function and stress responses. For instance, in mouse models, α-amylase activity can indicate salivary gland dysfunction. Moreover, α-amylase expression is also used to investigate neurodegenerative diseases like Alzheimer's disease, where its expression in neurons may be linked to glycogenolysis and neuronal activity.