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Bovine Extracellular Calcium-Sensing Receptor (CASR) ELISA Kit-Sandwich

Cat. No.EK12F85

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Bovine Extracellular Calcium-Sensing Receptor (CASR) ELISA Kit-Sandwich is designed for the quantitative determination of Bovine Extracellular Calcium-Sensing Receptor (CASR) in serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Bovine CASR.
Target Species Bovine
Species Reactivity Bovine
Detection Range 0.156-10 ng/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 10%
Assay Time Around 270 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids.

Target Information

Bovine Extracellular Calcium-Sensing Receptor is encoded by the CASR gene in cattle. It is predominantly expressed in the parathyroids and kidney. It is a family C G-protein-coupled receptors, which regulates systemic calcium (Ca2+) homeostasis that is critical for many physiological, calciotropical, and noncalciotropical outcomes in multiple organs. It allows regulation of parathyroid hormone (PTH) secretion and renal tubular calcium re-absorption in response to alterations in extracellular calcium concentrations.

Target/Biomarker Bovine CASR
Target Synonym calcium sensing receptor; BoPCaR1; extracellular calcium-sensing receptor; PCaR1; calcium-sensing receptor (hypocalciuric hypercalcemia 1, severe neonatal hyperparathyroidism); parathyroid Cell calcium-sensing receptor
Gene ID 281038
UniProt ID P35384

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Gorkhali, R. et al. Extracellular calcium alters calcium-sensing receptor network integrating intracellular calcium-signaling and related key pathway. Scientific reports. 2021, 11: 20576.
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