Recombinant Mouse Ephrin-A4 (EFNA4), C-Fc

Mouse Ephrin-A4, or EFNA4, is a protein expressed in various cell types, involved in cell signaling and tissue development. In mouse studies, EFNA4 is explored for its roles in nervous system development and diseases. EFNA4 interacts with eph receptors to regulate cell-cell interactions, axon guidance, and synaptic plasticity. In the developing brain, EFNA4 signaling is crucial for the establishment of precise neural connections and the formation of functional neural circuits. Dysregulation of EFNA4 has been implicated in neurodevelopmental disorders, such as autism spectrum disorders and schizophrenia, where aberrant neural connectivity is a common feature. Additionally, EFNA4 is involved in the pathogenesis of certain cancers, where it can influence tumor cell migration and invasion. Research on EFNA4 continues to uncover its diverse functions in different biological contexts and to identify potential therapeutic targets for modulating its activity in disease settings.