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Recombinant Guinea Pig Transthyretin (TTR), N-His
Product Overview
BioVenic's Recombinant Guinea Pig Transthyretin (TTR), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 16.2 kDa. The purity is> 90%.
Specifications
Target Information
Guinea pig Transthyretin (TTR) is a 55 kDa tetrameric protein primarily synthesized by the liver, choroid plexus, and retinal epithelial cells. It plays a crucial role in the transport of thyroid hormones and retinol (vitamin A) in the body. TTR is also involved in the regulation of various physiological processes and has been implicated in several diseases, including neurodegenerative disorders and amyloidosis. In guinea pigs, TTR may contribute to neuroprotection and promote nerve regeneration following injury. Additionally, TTR is a key player in the pathogenesis of transthyretin amyloidosis (ATTR), where genetic mutations or environmental factors can cause TTR to misfold and aggregate, leading to tissue damage. Understanding TTR's function in guinea pigs can provide insights into its role in human diseases and potential therapeutic applications.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10 mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.