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Recombinant Mouse Kallikrein-7 (Klk7), N-His-GST
Product Overview
BioVenic's Recombinant Mouse Kallikrein-7 (Klk7), N-His-GST is a recombinant protein expressed from E.coli. Its predicted molecular weight is 51.4 kDa. The purity is> 97%.
Specifications
Target Information
Mouse Kallikrein-7 (Klk7) is a member of the kallikrein family of serine proteases. It is involved in various physiological processes, including the regulation of blood pressure, inflammation, and skin desquamation. In the mouse epidermis, Klk7 plays a key role in the degradation of corneodesmosomes, which are structures that maintain the cohesion of the stratum corneum. By cleaving these structures, Klk7 facilitates the shedding of the outermost layer of skin cells, a process essential for normal skin turnover and barrier function. This activity is particularly important in conditions such as psoriasis, where impaired desquamation leads to scaling and thickened skin.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10 mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.