This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Recombinant Rabbit Cathepsin K (CTSK), N-His
Product Overview
BioVenic's Recombinant Rabbit Cathepsin K (CTSK), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 27.3 kDa. The purity is> 95%.
Specifications
Target Information
Rabbit Cathepsin K (CTSK) is a lysosomal cysteine protease that plays a crucial role in bone metabolism. In rabbits, CTSK is highly expressed in osteoclasts and is essential for bone resorption. It degrades collagen in the bone matrix, contributing to the remodeling process. Additionally, CTSK has been implicated in various pathological conditions. For instance, in a rabbit model of granulomatous and cavitary pathology, CTSK expression was significantly upregulated, contributing to tissue remodeling and collagen turnover. This suggests that CTSK may be a potential therapeutic target for diseases involving abnormal bone resorption or tissue fibrosis.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10 mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.