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Recombinant Mouse CD276 Antigen (CD276), C-His

Cat. No.AP2C775

Product TypeAnimal Proteins

Size

Product Overview

BioVenic's Recombinant Mouse CD276 Antigen (CD276), C-His is a recombinant protein expressed from Human Cells. Its predicted molecular weight is 34.0 kDa. The purity is>90%.

Specifications

Type Recombinant Protein
Species Mouse
Expression System Human Cells
Purity >90%
Endotoxin < 1.0 EU/μg
Predicted Molecular Weight 34.0 kDa
Physical State Lyophilized
Formulation 0.01 mol/L PBS (pH 7.2) containing 0.2% (w/v) Procline-300.

Target Information

Mouse CD276 Antigen, or CD276, is an antigen expressed on immune cells, involved in immune response regulation. In mouse studies, CD276 is explored for its roles in immune cell interactions and immune regulation. CD276 has been identified as a member of the immunoglobulin superfamily and functions as a costimulatory molecule. It can interact with its receptor on T cells to modulate their activation and function. In the context of cancer, CD276 expression has been associated with tumor immune evasion, as it may inhibit the activity of cytotoxic T cells. Conversely, in autoimmune diseases, CD276 may contribute to the pathogenic immune responses by enhancing the activation of autoreactive T cells. Therefore, understanding the dual roles of CD276 in different disease settings is essential for developing targeted therapies that can either enhance or suppress immune responses as needed.

Protein Mouse CD276 Antigen (CD276)
Protein Synonym B7 homolog 3; Costimulatory molecule; CD276
Gene ID 102657
UniProt ID Q8VE98

Shipping and Storage

This product is shipped with ice packs. Lyophilized protein can be stored at -20°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquot the reconstituted solution to minimize freeze-thaw cycles.
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