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Recombinant Canine Programmed Cell Death 1 (PDCD1), C-His

Cat. No.AP7F461

Product TypeAnimal Proteins

Size 100 μg

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Product Overview

BioVenic's Recombinant Canine Programmed Cell Death 1 (PDCD1), C-His is a recombinant protein expressed from HEK293 Cells. Its predicted molecular weight is 17.7 kDa. The purity is>85% (SDS-PAGE). The endotoxin level is <1 EU/μg (LAL).

Specifications

Type Recombinant Protein
Species Canine
Expression System HEK293 Cells
Biological Activity Active
Purity >85% (SDS-PAGE)
Endotoxin <1 EU/μg (LAL)
Predicted Molecular Weight 17.7 kDa
Physical State Lyophilized
Formulation PBS, pH 7.4.

Target Information

Programmed cell death 1 is encoded by the PDCD1 gene in dogs. Interruption of the programmed death 1 (PD-1) / programmed death ligand 1 (PD-L1) pathway is an established and effective therapeutic strategy in human oncology and holds promise for veterinary oncology.

Protein Canine Programmed Cell Death 1 (PDCD1)
Protein Synonym programmed cell death 1, PD-1, programmed cell death protein 1, programmed death 1
Gene ID 486213

Shipping and Storage

This product is shipped with dry ice. Avoid repeated freezing and thawing. Store for 12 months at -20°C or -80°C.

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquote the reconstituted solution to minimise freeze-thaw cycles.

References

  1. Choi, J. W. et al. Development of canine PD-1/PD-L1 specific monoclonal antibodies and amplification of canine T cell function. PloS one. 2020, 15: e0235518.
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