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Recombinant Mouse Lysyl Oxidase Homolog 2 (Loxl2), N-His
Product Overview
BioVenic's Recombinant Mouse Lysyl Oxidase Homolog 2 (Loxl2), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 13.0 kDa. The purity is> 95%.
Specifications
Target Information
Mouse Lysyl Oxidase Homolog 2 (Loxl2) is an enzyme that plays a significant role in the remodeling of the extracellular matrix (ECM). It catalyzes the oxidative deamination of lysine residues in collagen and elastin, promoting the formation of covalent cross-links that stabilize the ECM. Loxl2 is highly expressed in tissues undergoing active remodeling, such as the developing embryo, wound healing sites, and tumor stroma. In mouse models, Loxl2 deficiency leads to impaired wound healing and abnormal tissue development.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 20 mM Tris, 150 mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.