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Recombinant Bovine Splicing Factor 3B Subunit 3 (SF3B3), N-His
Product Overview
BioVenic's Recombinant Bovine Splicing Factor 3B Subunit 3 (SF3B3), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 42.6 kDa. The purity is>85% (SDS-PAGE).
Specifications
Target Information
Bovine splicing factor 3B subunit 3 (SF3B3) is essential for pre-mRNA splicing as part of the SF3B complex within the spliceosome. It facilitates the assembly of the 'A' complex by binding U2 snRNP to the branchpoint sequence in pre-mRNA, crucial for accurate splicing. Additionally, SF3B3 may play a role in the 'E' complex assembly and is involved in the minor U12-dependent spliceosome, which splices rare nuclear pre-mRNA introns, contributing to gene expression regulation in cattle.
Spliceosome-associated protein 130 (SAP 130)
Shipping and Storage
This product is shipped with dry ice. It is recommended to aliquot as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months. Avoid repeated freezing and thawing.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimise freeze-thaw cycles.