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Recombinant Chicken G2/mitotic-Specific Cyclin-B2 (CCNB2)
Product Overview
BioVenic's Recombinant Chicken G2/mitotic-Specific Cyclin-B2 (CCNB2) is a recombinant protein expressed from E.coli. Its predicted molecular weight is 44.7 kDa. The purity is>85% (SDS-PAGE).
Specifications
Target Information
Chicken G2/mitotic-Specific Cyclin-B2 (CCNB2) is a critical regulator of the cell cycle, particularly involved in the G2/M phase transition. It forms a complex with CDK1, which is essential for the initiation of mitosis. CCNB2 is synthesized during the G2 phase and degraded during mitosis, ensuring proper cell cycle progression. In chickens, CCNB2 plays a significant role in embryonic development, tissue regeneration, and feather growth. Abnormal expression of CCNB2 can lead to cell cycle dysregulation and is associated with various cancers, where it promotes tumor growth and metastasis by enhancing cell proliferation. CCNB2 is also implicated in the regulation of immune responses and viral infections, making it a potential target for therapeutic interventions in cancer and other diseases.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in deionized sterile water to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.