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Rabbit Anti-Rat Histidine Rich Glycoprotein (HRG) Polyclonal Antibody

Cat. No.VD3N860

Product TypeVeterinary Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for rat histidine rich glycoprotein. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of rat histidine rich glycoprotein.

Specifications

Application WB; IHC; ICC; IP
Clonality Polyclonal
Classification Primary Antibody
Clone C2N260
Host Rabbit
Target Species Rat
Species Reactivity Rat
Specificity Rat Histidine Rich Glycoprotein
Isotype IgG
Immunogen Recombinant protein of rat histidine rich glycoprotein
Purification Purified by Protein A
Concentration 0.5 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline, pH 7.4, with 50% glycerol
Physical State Liquid

Target Information

Rat granulin (GRN) is a 67-kDa secreted glycoprotein ubiquitously expressed in rat tissues, with elevated levels in liver, lung, and immune cells (macrophages, neutrophils). It is proteolytically processed into bioactive peptides that regulate rat-specific physiological processes: tissue repair, inflammatory resolution, macrophage activation, and epithelial cell proliferation. Beyond tissue homeostasis, it modulates lysosomal function and extracellular matrix remodeling, supporting wound healing and organ regeneration in rats. Dysregulated expression associates with hepatic fibrosis, pulmonary inflammation, and tumor progression in rat models. As a multifunctional mediator of tissue repair and inflammatory responses, rat GRN is a critical target for studying fibrotic pathobiology, inflammatory disorders, and regenerative medicine therapeutics.

Target Rat Histidine Rich Glycoprotein
Target Synonym HPRG; HRGP; Histidine-Proline Rich Glycoprotein; Thrombophilia Due To Elevated HRG
Gene ID 29143
UniProt ID P23785

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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