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Rabbit Anti-Mouse Interleukin 2 Receptor Alpha (IL2Ra) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse interleukin 2 receptor alpha. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse interleukin 2 receptor alpha.
Specifications
Target Information
Mouse interleukin 2 receptor alpha (IL-2Rα, CD25) is a 55-kDa transmembrane glycoprotein predominantly expressed on activated mouse T cells, regulatory T cells (Tregs), and subsets of B cells, natural killer (NK) cells, and dendritic cells. As a key component of the high-affinity IL-2 receptor complex (αβγ), it enhances IL-2 binding affinity, initiating downstream signaling that regulates T cell proliferation, survival, and differentiation. Critical for murine adaptive immune homeostasis, it promotes effector T cell expansion during infection and maintains Treg-mediated immune tolerance. Dysregulated expression contributes to autoimmune diseases, immunodeficiencies, and cancer. As a selective marker of activated and regulatory T cells, mouse IL-2Rα is a critical target for studying immunology, inflammatory disorders, and immunotherapeutic development.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.